McDreamy (Patrick Dempsey), Burke, Sloan (Eric Dane). Everyone has a favorite doctor to pair the main cast with. But out of all the romantic interests that Shonda Rhimes created, one rose above the pack.
"I was so in love with Denny — not the actor. Like, literally, the actor didn't exist for me," Rhimes admitted. "He almost wasn't allowed to talk to me. I was so in love with Denny it was shameful. I joked on the blog he should have a restraining order that couldn't come within 50 feet because I was so in love with him." Even though Denny's (Jeffrey Dean Morgan) death was planned from the beginning, he had one of the most frustrating deaths in "Grey's Anatomy." Morgan had been cast with the full knowledge that he wouldn't last the season, but his vulnerability and heartfelt love story with Izzie (Katherine Heigl) made him a fan favorite. His death was made all the more devastating at the end of Season 2 because he was so likable. Luckily for Morgan, that wasn't exactly curtains for the character. He was brought back intermittently through the series and was so appreciated that the crew didn't even mind the odd ghost story that allowed his return. In a show with a vast array of romantic men who could never exist in real life, Denny was one in a million.