Throughout the 10 seasons of "Friends," viewers receive regular reminders that Monica lost a ton of weight since her teen years. Following a slew of flashback moments, which show a much larger version of Monica, it's revealed that her drastic transformation was spurred by Chandler insulting her size at a Geller family Thanksgiving.

However, several fans believe that Monica's weight loss may have resulted in some new issues. On Reddit, u/Theluckygal pointed out how, in flashback scenes that depict Monica at her old weight, she's never shown cleaning or organizing anything. "Maybe at fat camp she was experimented for a drug that helped her lose weight but it messed up her hormones that resulted in OCD (google hormones+ocd) & infertility," they said. 

While some commenters on the thread agreed, others like u/JH4227 provided a simplified theory that Monica just has an addictive personality. They said, "Basically, she traded one addiction/compulsion for another. No experimental drugs necessarily required."

It should be noted that these theories are all pure speculation based on the observations of these fans, but for those looking to dig deep into the psychology of the characters on "Friends," it's certainly something to think about.