After the foursome leaves Doug, the film gives viewers a glimpse into how everyone's lives have changed. Hunter no longer wears his cone, but continues to be a therapy dog. He and Maggie are also now in a relationship, getting some strange approval from Hunter's elderly companions. Maggie doesn't live with her uncaring owner anymore and has taken a new position as a police dog, where she's thriving thanks to her amazing sniffing skills.

Bug no longer exists as a stray and now lives a new life with his new companion Riley (Mikayla Rousseau) — the missing Girl Scout the group helped find. He has found a home where he truly feels loved and even has a new couch lover. As for Reggie, he decides to stay a stray and take on a new role of helping other strays become acclimated to their new life. He's seen giving the same rules that Bug does at the beginning of the film, but changes the last one to remind other canines that they are not alone. Despite Bug and Reggie switching lifestyles, though, they still find time to hang out, cuss out the mailman, and play with much nicer humans. And as for Doug, well, viewers see in a brief mid-credits scene that he's being told by a doctor that his injuries are severe and that they couldn't re-attach his penis –- which leads to him letting out a massive scream.