On the r/southpark subreddit, fans discussed one such scene from Season 18, Episode 7 ("Grounded Vindaloop"), which sees five central cast members from the series brought into the real world. After an entire episode of VR-related hijinks, friends Stan, Kyle, Kenny, Cartman, and Butters (all five of whom are voiced by creators Trey Parker and Matt Stone) think they've finally got things sorted when suddenly they find themselves in the real world.
u/leejtam asked their fellow "South Park" fans what they thought of the real-life versions of the characters in a popular thread. The appropriately named u/swisscheesefarts scored the top comment. "It was a good detail by them to not show Kenny's mouth," they observed. "Then I thought about how cool it would be to be these kids and be able to tell your friends that you're one of the South Park kids."
Though they're only small parts, there would definitely be some social cache in being in a popular TV show, particularly one that's meant for older kids and adults. "Way better than the one where they're on the boat and basically adults," observed u/itshukokay. The user is referring to Season 16, Episode 6 ("I Should Have Never Gone Ziplining"), which featured a live-action reenactment of the boys' "traumatic rescue" at the tail end of the episode. Humorously, all four characters were just played by adults wearing the iconic winter headwear of the kids.