DiNozzo first approaches Dr. Jeanne Benoit not out of interest in her as an individual, but in order to investigate her father, René Benoit, an arms dealer known as La Grenouille. Given the nature of his flirtations with Jeanne being for work, DiNozzo introduces himself to her under the alias Tony DiNardo.

That said, what begins simply as an undercover mission eventually blossoms into a bona fide romance. The two experience many of the typical ups and downs of a new couple, from hesitancy in professing their love for one another, to discussing cohabitation as a next step. While those moments are predicated upon genuine interest, the fact that Jeanne knows Tony not as DiNozzo, but as DiNardo, perpetually hangs over their relationship.

Likely surprising no one, the relationship implodes upon Jeanne learning that it was built upon a lie. Jeanne eventually marries another doctor named David Woods, and the two even aid the Naval Criminal Investigative Service years later when they travel to South Sudan. During their few reunions, DiNozzo attempts to make amends with Jeanne, but the gulf between the two of them remains too great to close, even after a heartfelt apology from DiNozzo. 

While they may have shared genuine moments with one another, each and every one of those moments was colored by deception. The relationship, then, is easily DiNozzo's worst.