One of the most important relationships in The Sopranos, if not the most important relationship, is between mob boss Tony Soprano (James Gandolfini) and his therapist, Dr. Jennifer Melfi (played by Lorraine Bracco). For seven years, the two danced around each other in Melfi's oval office, as the therapist was often entranced and sometimes repulsed by her gangster client. Making things even more complicated, Tony was sometimes in love and sometimes sick of his therapist. Through it all, the personal and professional connection very nearly ended on more than one occasion, but the two always seemed to find their way back to each other.
Then, in the penultimate episode of the series, Melfi comes to a realization after a colleague encourages her to read up on how Tony, as a sociopath, might simply be taking advantage of her. Convinced that he's been using her, Melfi cuts Tony off during a tense final session. Throughout the war with Phil Leotardo (Frank Vincent) and the Lupertazzi crime family, Tony doesn't attempt to call or contact her, and as far as we know, he considers their relationship over, just as she does. If Tony made it out of the series alive, it's possible he would've he looked for similar care at some point in the future, but Melfi seemed hellbent on shutting him out of her life.