With Josh Meyers' last appearance on "That '70s Show" coming in 2006, his next major role came in the 2008 comedy "College Road Trip," in which he stars alongside Raven-Symoné and Martin Lawrence. In the film, Meyers plays Deputy Stuart, a police officer and co-worker of James Porter (Lawrence). He followed that up with another comedy, the 2009 mockumentary "Brüno," in which he stars as Kookus Mansfield alongside Sacha Baron Cohen.

Meyers returned to television in 2012 with guest appearances in the comedies "Are you There, Chelsea?" and "Breaking In." He followed it up with guest appearances in 2013 in the TV shows "Newsreaders" and "The Mindy Project." He also continued to preform in films like "Inventing Adam," "Straight A's," and the Steven Soderbergh film "Behind The Candelabra." All these films happened in 2013, making it a prolific year for Myers. 

2014 saw Meyers join the Amazon Prime series "Red Oaks," alongside Jennifer Grey, Richard Kind, and Paul Reiser. Over the course of the show's three seasons, Meyers was a key part of the show, playing Barry, the videographer at the titular Red Oaks country club in New Jersey.

Over the past few years, Meyers has also made recurring appearances on "Late Night with Seth Meyers" as a satirical version of the California governor Gavin Newsom. His last role was an appearance on the NBC science-fiction series "Quantum Leap."