In 2018 Peña reprised the role of Luis for "Ant-Man and The Wasp," but before the sequel premiered, Peña had once again gained praise for his role in Ridley Scott's "The Martian." He also appeared in Disney's "A Wrinkle in Time" as Red, better known to readers as the villainous Man With the Red Eyes.

Since "Ant-Man and The Wasp," Peña has continued to take on roles across the board. He played Cole in the kid-friendly "Dora and the Lost City of Gold," and the mysterious Mr. Roarke in the 2020 horror remake of "Fantasy Island." In addition, Peña took on the role of actual DEA agent Enrique 'Kiki' Camarena on "Narcos: Mexico," a role that reunited him with "Star Wars" actor Diego Luna. Luna directed Peña in 2014's "Cesar Chavez," in which Peña portrayed the titular American civil rights activist.

Earlier this year, Deadline announced the addition of Michael Peña to the upcoming sci-fi epic, "Moonfall." The film also stars Halle Berry, Patrick Wilson, Eme Ikwuakor, Charlie Plummer, and Donald Sutherland.