Of course, "Family Guy" hasn't been afraid to throw shade right back at "The Simpsons." In the episode "The Juice is Loose," Peter Griffin (voiced by Seth MacFarlane) befriends O.J. Simpson (Mike Henry), and at one point in the story, Mayor West (Adam West) says, "We don't want you in our town, Simpson. We don't love you like we did in 1993." The scene then cuts to Homer Simpson, who gives his trademarked "D'oh!" While it would seem there's some bad blood between the two productions, Matt Groening and "Family Guy" creator Seth MacFarlane enjoy the friendly rivalry they've established.
In a 2006 interview with The A.V. Club, Groening was asked about those "Family Guy" ripoff rumors, to which he responded, "The rivalry is very affectionate. Seth MacFarlane, the creator of Family Guy, is a good guy and he does great work, and I certainly have no problem with the perceived competition. If anything, we have the same kind of competition that Pugsley Addams and Eddie Munster had in the old days. They duked it out a few times, and so did Seth and I, but that's probably before your time."
This interview took place before the infamous "Family Guy" and "The Simpsons" crossover, where the two shows brought their grievances with one another to the forefront. The episode ended with a massive fistfight between Peter Griffin and Homer Simpson, but it sounds like things are much more cordial behind the scenes.
