Let's just get one thing clear: Yes, that is absolutely a man made of bees. Better known under the unsurprising pseudonym "Swarm," Fritz von Meyer was a Nazi scientist who stumbled across a colony of mutant bees after the end of World War II. Von Meyer attempted and failed to control these bees, who consumed him alive and absorbed him into their hive mind. This not only merged their consciousnesses, but they also gave him the ability to control them at will.
All of this is explained in "Champions" Vol. 1 #15, a story in which Swarm takes on a team of heroes including Angel, Black Widow, Ghost Rider, Hercules, Iceman, and Dark Star. Since then, however, von Meyer and his bothersome bees have become a stalwart enemy of Spider-Man, first facing him in "Peter Parker, the Spectacular Spider-Man" Vol. 1 #36. More recently, in "Ant-Man" Vol. 2, he's teamed up with Scott Lang to take down the Bug Lords, who are exactly what they sound like.
As you might've guessed, Swarm isn't exactly the most dour comic book villain out there. Indeed, his latest stories have been a lot of fun, often leaning into the character's archness as far as possible. If ever a future "Spider-Man" movie needed a colorful and amusing secondary antagonist to stir up some trouble on the side, Swarm would be just the guy/horrific mass of bees for the job.
