Thankfully, most of the characters in "What If...?" Episode 7 were voiced by their original MCU actors. Chris Hemsworth returned for Thor, Tom Hiddleston for Loki, and Natalie Portman for Jane Foster. Some cameo roles featured original stars like Karen Gillan and Jeff Goldblum, who lent their voices to Nebula and the Grandmaster. However, some actors did not voice their original characters, and Rene Russo was one of them. In Episode 7, Frigga was voiced by Josette Eales, an actress with a relatively short resume in the business, per IMDb.
Russo hasn't spoken out about not reprising her role in "What If...?" but she's hardly the first MCU star to be absent from the project. In Episode 7 alone, a handful of other characters were voiced by someone other than their live-action portrayer. Captain Marvel, Hogun, Fandral, Volstagg, and Drax were all voiced by someone other than their original MCU star. While it would have been great to hear Russo's voice again, we're just happy the Queen of Asgard had another appearance in a Marvel Studios project.