Marino frequently stars on shows produced by Abominable Pictures. Founded by Jonathan Stern, the company has made many shows for Adult Swim, plus a few movies. Abominable produced "Diggers," a 2006 film written by Marino and starring his "Wet Hot" co-star Paul Rudd.
Marino also had a featured role in "Childrens Hospital," the Adult Swim hospital soap parody. Originally created by Rob Corddry as a web show, it was picked up by Adult Swim in 2009. Marino played Dr. Glenn Richie, a character he'd originated in "The Ten." Richie was the hospital playboy, and made out with most characters at least once. Richie appeared on the Netflix spin-off of the show, "Medical Police," where he's in private practice.
Marino also starred in season one of "Burning Love," a "Bachelor" parody created by Marino's wife, Erica Oyama. Marino directed the show in addition to playing dimwitted firefighter Mark Orlando.