In a 2012 thread in the r/IAmA subreddit (the same year that the Schrute Facts meme took off), Rainn Wilson hosted an AMA session in which user u/superme33 asked what he felt about Dwight becoming a meme. In response, the actor seemed ecstatic. "I love that Dwight is a bobble-head, a graffiti, a meme and an icon of weirdness for a generation," Wilson said in response to the question. "So thankful to the fans for making Dwight a legend of TV." And why wouldn't he be happy about it? It's likely that even a large portion of people who have never watched "The Office" still recognize the character that Wilson played on the show for nine seasons.
In the same AMA, user u/MeVersusShark asked if the "Office" star worried about being typecast after becoming so well known for playing Dwight. The actor explained that he had accepted that he would always be tied to the iconic character. "I will always be known for Dwight and I'm fine with that," Wilson wrote. "I have always been an actor and i'll [sic] just keep acting and people will see my range BUT they'll still say 'hey, there's Dwight from The Office!'"
It would seem that the actor is perfectly happy with the success of his most popular role, and he doesn't begrudge the fact that he'll forever be associated with Dwight.